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Brand analysis: UK polynucleotides, August 2026

No brand holds this category outright. A single clinic separates the leading two names, and the seven brands ranked below are not one product class.

By Rare.Monitor analyst team Published 5 August 2026

August 2026 / Aesthetics / UK

Medical Aesthetics Polynucleotides Skin Boosters Self-Pay Healthcare

Top 3 brands by share of mentions

01Vitaran31.1%
02Plinest Register to see
03Nucleofill Register to see

Source: Rare.Monitor, August 2026. 6,161 UK clinics offering polynucleotides audited (n=1,168 brand-naming). Company shown is the brand owner where ownership could be confirmed, not the UK distributor.

RARE

Polynucleotide-category injectable products only. Topical kits, injectable lipolytics and hyaluronic acid bioremodellers are separate categories. Brand names are counted as clinics publish them, not as verified classes.

Brands tracked in this analysis

Ameela
Nucleofill
Plenhyage XL
Plinest
PolyPhil (formerly PhilArt)
Rejuran
Vitaran

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More on this analysis

Which polynucleotide brands are named most often by UK clinics?

Vitaran leads, named on 31.1% of the 1,168 UK clinics that name a polynucleotide-family injectable brand on their own website in August 2026. Plinest follows on 31.0%, a single clinic behind, then Nucleofill on 22.3%, Ameela on 15.1% and PolyPhil (formerly PhilArt) on 9.2%. Rejuran on 6.6% and Plenhyage XL on 4.5% complete the seven tracked brands. The seven are not one verified formulation class: some carry polynucleotide labelling, some polydeoxyribonucleotide, and several brand names cover more than one product. Source: Rare.Monitor, August 2026.

How many UK clinics offer polynucleotide treatments?

Rare.Monitor recorded 6,161 approved, searchable UK clinics offering polynucleotides in August 2026, of which 1,168 (18.96%) name at least one of seven tracked polynucleotide-family injectable brands on their own website. The base covers England, Scotland and Wales. Northern Ireland clinics are not included and Ireland is outside this read, so the figures are a conservative UK count rather than a full four-nation total. Products in the same treatment category delivered topically or by microneedling, and injectable lipolytics, are excluded. Source: Rare.Monitor, August 2026.

Does share of mentions mean market share or sales?

No. Share of mentions measures how many UK clinics name a brand in the copy they publish on their own website, which is a measure of brand visibility. It is not a measure of units sold, treatments delivered or revenue, and no sales or volume figure should be inferred from it. It also counts brand names as clinics write them, not specific product variants, so a clinic naming Rejuran or Ameela is not telling you which product in that range it uses. Source: Rare.Monitor, August 2026.

Why do the polynucleotide brand percentages add up to more than 100%?

Each percentage is the share of the 1,168 brand-naming UK clinics that name that brand owner's products, and a clinic naming brands from two different brand owners counts once for each. The seven brand counts sum to 1,399 against a cohort of 1,168, or 119.8%, rather than 100%. Two brands from the same owner count once, which is why Plinest and unbranded Mastelli mentions collapse into one Mastelli count. Clinic counts are deduplicated by clinic name and postcode, the same rule used in the UK dermal filler and medical-grade skincare rankings. Source: Rare.Monitor, August 2026.

Brand analysis: UK polynucleotides, August 2026

See the full ranking

6,049 UK Clinics Offer Polynucleotides

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